Description
Product Characteristics: AURKC, aurora kinase C, AIE2, AIK3, ARK3, AurC, STK13, aurora-C, aurora/IPL1-related kinase 3, aurora/IPL1/EG2 protein 2, serine/threonine kinase 13 (aurora/IPL1-like)
Target Information: This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]